Studio Mary Jane has announced an anime hentai adaptation of the visual novel "Onii-chan Asa made Zutto Gyutte Shite!" by company "Tinkle Position", which was released in 2018. The hentai is scheduled for February 2020. 

The protagonist has suffered from severe asthma since early childhood, and his four younger sisters - Sora, Akane, Kohaku, and Sumi - took turns sleeping with him every day to monitor his condition. Years passed and our heroes became adults, but the daily ritual remained. Every day one of the sisters stayed with him for the night. The parents were very concerned about their son's condition and decided to apply a modern method of treating all diseases - "cuddles". Now each of the sisters not only simply sleeps next to her brother, but also hugs him in her sleep and even sometimes has sex with him to increase the healing effect as much as possible...